Activation of Human Platelets by Misfolded Proteins
نویسندگان
چکیده
منابع مشابه
Activation of human platelets by misfolded proteins.
OBJECTIVE Protein misfolding diseases result from the deposition of insoluble protein aggregates that often contain fibrils called amyloid. Amyloids are found in Alzheimer disease, atherosclerosis, diabetes mellitus, and systemic amyloidosis, which are diseases where platelet activation might be implicated. METHODS AND RESULTS We induced amyloid properties in 6 unrelated proteins and found th...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2007
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.107.143479